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Dasheng Wang Selected Research

(1- (4- chloro- 3- nitrobenzenesulfonyl)- 1H- indol- 3- yl)- methanol

11/2009Targeting of the Akt-nuclear factor-kappa B signaling network by [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a novel indole-3-carbinol derivative, in a mouse model of hepatocellular carcinoma.
10/2009OSU-A9, a potent indole-3-carbinol derivative, suppresses breast tumor growth by targeting the Akt-NF-kappaB pathway and stress response signaling.
8/2007A potent indole-3-carbinol derived antitumor agent with pleiotropic effects on multiple signaling pathways in prostate cancer cells.

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Dasheng Wang Research Topics

Disease

18Neoplasms (Cancer)
01/2020 - 08/2007
5Prostatic Neoplasms (Prostate Cancer)
01/2014 - 08/2007
4Breast Neoplasms (Breast Cancer)
04/2019 - 04/2008
3Hepatocellular Carcinoma (Hepatoma)
06/2011 - 10/2007
2Acute Lung Injury
01/2021 - 04/2020
1Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder)
11/2021
1Inflammation (Inflammations)
01/2021
1Pulmonary Edema
01/2021
1Edema (Dropsy)
01/2021
1Drug Resistant Epilepsy
01/2018
1Epilepsy (Aura)
01/2018
1Adenocarcinoma
03/2013
1Starvation
03/2013
1Carcinogenesis
03/2013
1Infections
08/2012
1Hypoxia (Hypoxemia)
11/2011
1Triple Negative Breast Neoplasms
11/2011
1Mast Cell Activation Disorders (Mast-Cell Disease)
05/2010
1Tularemia
12/2009
1Neoplasm Metastasis (Metastasis)
11/2009
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2008
1B-Cell Lymphoma (Lymphoma, B Cell)
10/2007

Drug/Important Bio-Agent (IBA)

5Biomarkers (Surrogate Marker)IBA
11/2011 - 08/2007
4Celecoxib (Celebrex)FDA Link
04/2019 - 04/2008
3Phosphotransferases (Kinase)IBA
11/2021 - 12/2009
3Proteins (Proteins, Gene)FDA Link
01/2021 - 04/2008
3OSU 03012IBA
04/2019 - 04/2008
3Protein Kinases (Protein Kinase)IBA
04/2019 - 04/2008
3(1- (4- chloro- 3- nitrobenzenesulfonyl)- 1H- indol- 3- yl)- methanolIBA
11/2009 - 08/2007
3indole-3-carbinolIBA
11/2009 - 08/2007
2Interleukin-6 (Interleukin 6)IBA
01/2021 - 11/2011
2OSU-2SIBA
01/2020 - 06/2011
2TamoxifenFDA LinkGeneric
04/2019 - 04/2008
2Phosphatidylinositols (Phosphatidylinositol)IBA
04/2019 - 04/2008
2Estrogen ReceptorsIBA
04/2019 - 04/2008
2Pharmaceutical PreparationsIBA
01/2016 - 11/2011
2Histone Deacetylase InhibitorsIBA
01/2016 - 10/2007
2Glucose (Dextrose)FDA LinkGeneric
03/2013 - 03/2011
2Antineoplastic Agents (Antineoplastics)IBA
06/2011 - 08/2007
2NF-kappa B (NF-kB)IBA
11/2009 - 10/2009
2Succinic Acid (Succinate)IBA
09/2009 - 07/2009
1Calmodulin (Calcium-Dependent Activator Protein)IBA
11/2021
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
11/2021
1AcidsIBA
11/2021
1CytokinesIBA
01/2021
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2021
1LipopolysaccharidesIBA
01/2021
1InterleukinsIBA
01/2021
1Hydrogen Sulfide (Sulfide, Hydrogen)IBA
04/2020
1CASP8 and FADD-Like Apoptosis Regulating Protein (FLIP-S)IBA
03/2016
1Endoplasmic Reticulum Chaperone BiPIBA
03/2016
1ThioredoxinsIBA
03/2016
1Small Interfering RNA (siRNA)IBA
01/2014
1Vitamin EFDA LinkGeneric
03/2013
1Tocopherols (Tocopherol)IBA
03/2013
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
03/2013
1OSU-CG5IBA
03/2013
1Adenosine Triphosphate (ATP)IBA
03/2013
1NAD (NADH)IBA
03/2013
1Anti-Bacterial Agents (Antibiotics)IBA
08/2012
1Fatty Acids (Saturated Fatty Acids)IBA
11/2011
1Chloroquine (Aralen)FDA LinkGeneric
11/2011
1Transcription Factors (Transcription Factor)IBA
11/2011
1Adenosine Monophosphate (AMP)IBA
11/2011
1Cadherins (E-Cadherin)IBA
11/2011
1OSU-53IBA
11/2011
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
11/2011
1Nuclear Respiratory Factor 1IBA
11/2011
1Fingolimod Hydrochloride (FTY720)FDA Link
06/2011
1Sphingosine-1-Phosphate ReceptorsIBA
06/2011
1Immunosuppressive Agents (Immunosuppressants)IBA
06/2011
1Kruppel-Like Factor 6IBA
03/2011
1Deoxyglucose (2 Deoxy D glucose)IBA
03/2011
1Biological ProductsIBA
05/2010
1Histones (Histone)IBA
05/2010
1Biological Warfare AgentsIBA
12/2009
1Methanol (Carbinol)IBA
11/2009
1LuciferasesIBA
11/2009
1EnzymesIBA
10/2009
1Acetic Acid (Vinegar)FDA LinkGeneric
09/2009
1Extracellular Matrix ProteinsIBA
09/2009
1titanium silicide (TS-1)IBA
07/2009
1Androgen Receptors (Androgen Receptor)IBA
07/2009
1alpha-TocopherolFDA Link
07/2009
1ErbB Receptors (EGF Receptor)IBA
04/2008
1Inhibitor of Apoptosis ProteinsIBA
10/2007
1Baculoviral IAP Repeat-Containing 3 ProteinIBA
10/2007
1SurvivinIBA
10/2007
1Dihydrotachysterol (AT 10)IBA
08/2007

Therapy/Procedure

4Oral Administration
01/2016 - 10/2007
3Therapeutics
03/2011 - 08/2007
1Vagus Nerve Stimulation
01/2018
1Caloric Restriction
03/2013